Search results for "computational design"
showing 8 items of 8 documents
Knowledge formalization and recommendation in computational design synthesis for 4D printing
2022
Coined in 2013, 4D printing is considered as a promising technology that combines additive manufacturing (AM) processes and smart materials (SMs). Through this technology objects can change over time in terms of functionalities, shape, or properties under the effect of energy stimulation. Although AM processes allow shape, hierarchical, functional, and materials complexities to the 3D objects, the conjunction with SMs provides much more freedom in designing adaptive/transformative structures. Over the last decade, a growing body of research with ad hoc proofs-of-concept have been proposed at the physical level (i.e., by using different AM processes with commercial or customized 3D printers …
Computational design of biological catalysts
2008
The purpose of this tutorial review is to illustrate the way to design new and powerful catalysts. The first possibility to get a biological catalyst for a given chemical process is to use existing enzymes that catalyze related reactions. The second possibility is the use of immune systems that recognize stable molecules resembling the transition structure of the target reaction. We finally show how computational techniques are able to provide an enormous quantity of information, providing clues to guide the development of new biological catalysts
EVALUATION OF THE COMBINED EFFECT OF VEGETATION AND NATURAL VENTILATION IN NEARLY ZERO ENERGY MULTI-STOREY BUILDINGS – nZE(ms)B
2020
Cooling load is the main cause of high energy consumption for tall buildings in tropical climates while the construction of tall buildings is an unavoidable practice due to land scarcity in metropolitan cities. In this regard, the use of natural ventilation (NV) in tall buildings can help reducing the energy consumption. However, this solution can also bring the problem of polluted air that may enter the space to be ventilated. If the air is passed through a system that can absorb pollutants and add more oxygen to the air, the problem may almost be solved. Building integrated vegetation (BIV) systems can help solving this problem. So, if the air entering buildings passes through dense veget…
Luigi Moretti, from history to parametric architecture
2018
In this article we aim to give new light on the thinking of Luigi Moretti, first to have formulated the concept of parametric architecture, comparing it with those of some contemporary architectural theorists and designers. The latest researches on materials and form-finding experiences have shown a new relationship between form and structure, Moretti understood it before the advent of the internet. Moretti's parameter stems from the architectural tradition, as Carpo sees relations between parametric design and history. Moretti’s Parametric architecture is interdisciplinary, open to science in ways that we are only now understanding. We, therefore, believe that recovering Moretti’s methods …
ChemInform Abstract: Computational Design of Biological Catalysts
2009
The purpose of this tutorial review is to illustrate the way to design new and powerful catalysts. The first possibility to get a biological catalyst for a given chemical process is to use existing enzymes that catalyze related reactions. The second possibility is the use of immune systems that recognize stable molecules resembling the transition structure of the target reaction. We finally show how computational techniques are able to provide an enormous quantity of information, providing clues to guide the development of new biological catalysts.
Prospective computational design and in vitro bio-analytical tests of new chemical entities as potential selective CYP17A1 lyase inhibitors
2019
[EN] The development and advancement of prostate cancer (PCa) into stage 4, where it metastasize, is a major problem mostly in elder males. The growth of PCa cells is stirred up by androgens and androgen receptor (AR). Therefore, therapeutic strategies such as blocking androgens synthesis and inhibiting AR binding have been explored in recent years. However, recently approved drugs (or in clinical phase) failed in improving the expected survival rates for this metastatic-castration resistant prostate cancer (mCRPC) patients. The selective CYP17A1 inhibition of 17,20-lyase route has emerged as a novel strategy. Such inhibition blocks the production of androgens everywhere they are found in t…
Session III - PARAMETRIC MODELLING AND VIDEO MAPPING_INTRODUCTION
2022
Virtual representation, free-form surface modelling techniques and numerical control manufacturing, with their intrinsic dynamic and interactive capabilities, have profoundly expanded and enriched the repertoire of geometric shapes, generating innovative design skills and creative languages. There is no doubt about the opportunities for exploration, contamination, relationships and overlapping of ideas, measurements and information, which the continuous evolution of expeditious, parametric and automatic procedures brings to the use of the many products of the information age. Adopting computation as a form of design is profoundly different from simply using tools geared toward increasing th…
The role of Artificial intelligence in architectural design: conversation with designer and researchers
2020
The proliferation of data together with the increase of computing power in the last decade has triggered a new interest in artificial intelligence methods. Machine learning and in particular deep learning techniques, inspired by the topological structure of neurons network in brains, are omnipresent in the IT discourse, and generated new enthusiasms and fears in our society. These methods have already shown great effectiveness in fields far from architecture and have long been exploited in software that we use every day. Many computing libraries are available for anyone with some programming skills and allow them to "train" a neural network based on several types of data. The world of archi…